Multiplate continuously records platelet aggregation. The attachment of platelets onto the Multiplate sensors generates an increase in impedance which is transformed into arbitrary aggregation units (AU) and plotted against time. Unlike other platelet function analyzers Multiplate displays and documents the aggregation tracings which provides the user with a qualitative assessment of platelet function and visual plausibility check.
Three parameters are calculated: The most important parameter is the area under the aggregation curve (AUC). It is affected by the total height of the aggregation curve as well as by its slope and is best suited to express the overall platelet activity. Two more parameters are calculated for research use: The aggregation is the height of the curve. The velocity is the maximum slope of the curve. As seen on the diagram on the right, two curves are assessed using the two independent sensors in the testcell. The parameters calculated by the software are the mean values of the parameters determined with each curve.
Multiplate® - the new standard for platelet diagnostics.