sensitive for aspirin, clopidogrel, IIb/IIIa antagonists, predictive for both transfusion requirements and thrombotic events*, positive experiences from a large number of clinical centers throughout Europe

*The largest study to date evaluating the clinical impact of clopidogrel resistance (n=1608) has shown that patients, stratified as inadequate responders according to Multiplate® analysis exhibited a 9.4 fold increased risk of stent thrombosis (Sibbing D et al. J Am Coll Cardiol 2008; 53(10):849-56). In a recent study Siller-Matula et al reported a superior predictivity for stent thrombosis for Multiplate® compared to the flow-cytometric VASP test (Multiple Electrode Aggregometry better predicts stent thrombosis than the VASP assay. J Thromb Haemost. 2009 Nov 23). The predictivity of Multiplate® analysis has also been demonstrated in neuroradiology (Mueller-Schunk S et al, AJNR 2008;29(4):786-9). Several studies have also shown that Multiplate® analysis is predictive for transfusion requirements in cardiac surgery (Rahe-Meyer N et al, Acta Anaesthesiol Scand. 2009 Feb;53(2):168-75; Rahe-Meyer N et al. Anesth Analg. 2008 Dec;107(6):1791-7; Mengistu AM et al, J Cardiothorac Vasc Anesth. 2008 Feb;22(1):40-6).